Anyone who has followed some of my threads would have seen the words “carrier oils and bio-availability”
What is a carrier oil?
Carrier oils “carry” essential oils into our skin or tissues and also into our blood stream depending on delivery method.
What does bio-availability mean?
This refers to the amount of a drug, that reaches the blood regardless of delivery method.
When using cannabis oil for medical purposes, it’s vital to get the most from your meds. Ingesting raw cannabis oil is effective but most of what’s ingested goes to waste as the bio-availability is so poor. Only around 20% of what’s taken orally actually gets absorbed and made use of. The other issue with ingesting raw oil is it’s extremely powerful and the high is intense. So to be clear, if you were to ingest 1 gram of straight cannabis oil (I do not recommend anyone does this!) you only benefit medically from around 200 mg.
Adding raw cannabis oil to carrier oils increases the bio-availability rate massively. In fact, up to around 80%. You can now see how important this is. You’re getting a much larger dose whilst saving huge amounts of oil.
There are many carrier oils that can be used but the most popular seem to be the following three…
- Flaxseed oil (organic cold pressed)
- Extra virgin olive oil
- Coconut oil
As i’m sure you are all aware, all three have their own health benefits, but which once is best suited for me?
Flaxseed
Flax is a Long-chained fatty acids. To my knowledge, these get pulled out of the gut and passed into the lymphatic system because the enzymes that act on them are found there, not in the liver.
Flax is amazing and is my choice of carrier oil for medical use, however, if treating an estogen-based cancer, such as some breast cancers, you should avoid this. My understanding is that estrogen-based breast cancer will proliferate in the presence of estrogen. The lignans in flaxseed oil are a functional match to estrogen. So by using Flaxseed oil as the carrier, it may encourage tumour cells to grow and proliferate which is why it should be avoided. Use extra virgin olive oil instead.
Extra Virgin Olive Oil
A good all round carrier oil and very easy to purchase from all big supermarkets
Coconut Oil
Targets the liver. For recreational use, this is awesome And is also the carrier of choice for liver cancer. When you're targeting liver cancer it's very important to use competitive inhibition. The cells you're targeting are right there in the liver where the enzymes that metabolise the THC are created, so you need lots going on to distract the enzymes, allowing the cannabinoids enough time to locate and attach to tumour cells.
What is Competitive Inhibition
THC is metabolised by particular enzymes in the liver. When THC is metabolised into 11-hydroxy-THC it's no longer medically usable, in other words it won't fight cancer cells.
There are a couple supplements you can take, amentoflavone and apigenin. These plant compounds are metabolised by those very same enzymes. The idea is to take supplements 30-45 min before the dose. This way it's expected that the liver enzymes won't be able to be created in enough numbers fast enough to get the cannabinoids when they eventually enter the liver. If we're successful, more cannabinoids get through, back out into the body and looking for attachment points.
We've created competition for the cannabinoids to inhibit the enzymes.
So now we have our supercharged cannabis oil, let's charge it a bit more with the Bio Bomb
Sunflower liquid Lecithin..
Lecithin is a yellow-brown coloured fatty substance found in all living things (it’s a gooey substance that makes up about a third of your brain). Lecithin contains choline, which is used throughout your entire body as a major ingredient in each and every cell membrane. Besides the fact that your brain absolutely loves this stuff, lecithin provides other benefits when it is included in cannabis infused oils.
First, lecithin gets more cannabinoids into your brain and other cells and it gets them there faster since, you know, your brain is made of the stuff. Second, lecithin increases the effectiveness of the cannabinoids as well as the intensity of the effect. Also, lecithin acts as an emulsifier in the infusion process, helping more cannabinoids to bond with the oil molecules.
Using size 00 capsule, use the guide below
20:1 = 1 g CCO + 16 g carrier oil + 4 g lecithin
1000 mg cannabinoids /21 capsules = 47 mg cannabinoids per capsule.
10:1 = 1 g CCO + 8 g carrier oil + 2 g lecithin
1000 mg /11 capsules = 91 mg cannabinoids per capsule
5:1 = 1 g CCO + 4 g carrier oil + 1 g lecithin
1000 mg/6 capsules = 167 mg cannabinoids per capsules
1. Mix your CO with your chosen carrier oil in a warm water bath.
2. Now add the Lecithin and mix well
3. Place in the fridge for 24 hrs but mix again after 12 hrs
4. Bring up to room temp and fill your capsules using a 1 ml/g syringe
Folks, i’m no expert, far from it, and I’ve put this together to the very best of my knowledge. I hope some of you find it useful
As normal, many thanks to Cajun and SS for the huge amount of info they share
Mon the Oil!
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